Frameline’s mission is to support, develop, and promote lesbian, gay, bisexual, transgender, and queer visibility through media arts. Through a variety of programs and activities, Frameline provides access to films and videos dealing with a wide variety of issues related to sexuality and gender.

Each year Frameline presents the San Francisco International Lesbian & Gay Film Festival, the world's oldest and largest event of its kind. Frameline brings the best in lesbian and gay films and videos to communities across the country through Frameline Distribution, the nation's only distributor solely dedicated to lesbian and gay film and video.